Interventions for Invasive non-typhoid Salmonella (iNTS)

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Age Cohort: 12 - 24 years

Health Promotion	Disease Prevention	Diagnostic	Curative	Rehabilitative	Palliative
Community Level
Community and mass media-based awareness campaign	Access to safe drinking water Use of improved sanitation Hand washing with soap Malaria prevention	Recognition of Invasive Non-typhoid salmonella signs and symptoms	Oral rehydration Antipyretics Immediate transfer to a higher-level health care facility
Primary Care
Health education on prevention and treatment of Invasive Non-typhoid salmonella	Access to safe drinking water Use of improved sanitation Hand washing with soap Malaria prevention	History Physical examination	Oral rehydration Antipyretics Immediate transfer to a higher-level health care facility
Referral Facility: General
Health education on prevention and treatment of Invasive Non-typhoid salmonella	Access to safe drinking water Use of improved sanitation Hand washing with soap	History Physical examination Anthropometric measurement Complete blood count Malaria test HIV test Serologic tests	Oral rehydration salts (ORS) solution Antibiotics IV fluids Anti-malaria treatment Nutritional support
Referral Facility: Specialist
Health education on prevention and treatment of Invasive Non-typhoid salmonella	Access to safe drinking water Use of improved sanitation Hand washing with soap	Blood culture Bone marrow culture Stool culture Lumbar puncture CSF analysis	Antibiotics Anti-malaria treatment IV fluid Nutritional support

Age Cohort: 5 - 11 years

Health Promotion	Disease Prevention	Diagnostic	Curative	Rehabilitative	Palliative
Community Level
Community and mass media-based awareness campaign	Good sanitation and hygiene practices Safe water supply Malaria prevention	Recognition of Invasive Non-Typhoid Salmonella (iNTS) signs and symptoms	Oral rehydration Antipyretics Immediate transfer to a higher-level health care facility
Primary Care
Health education on prevention and treatment of Invasive Non-typhoid salmonella	Access to safe drinking water Use of improved sanitation Hand washing with soap Malaria prevention	History Physical examination	Oral rehydration Antipyretics Immediate transfer to a higher-level health care facility
Referral Facility: General
Health education on prevention and treatment of Invasive Non-typhoid salmonella	Access to safe drinking water Use of improved sanitation Hand washing with soap Malaria prevention	History Physical examination Anthropometric measurement Complete blood count Malaria test HIV test Serologic tests	Oral rehydration salts (ORS) solution Antibiotics IV fluids Anti-malaria treatment Nutritional support
Referral Facility: Specialist
Health education on prevention and treatment of Invasive Non-typhoid salmonella	Access to safe drinking water Use of improved sanitation Hand washing with soap Malaria prevention	Blood culture Bone marrow culture Stool culture Lumbar puncture CSF analysis	Antibiotics Anti-malaria treatment IV fluid Nutritional support

Age Cohort: < 5 years

Health Promotion	Disease Prevention	Diagnostic	Curative	Rehabilitative	Palliative
Community Level
Community and mass media-based awareness campaign	Breastfeeding Good sanitation and hygiene practices Safe water supply Insecticide treated bed net Indoor residual spray	Recognition of Invasive Non-typhoidal Salmonella (iNTS) signs and symptoms	Oral rehydration Antipyretics Immediate transfer to a higher-level health care facility
Primary Care
Health education on good sanitation and hygiene practices including hand washing	Good sanitation and hygiene practices Perennial malaria chemoprevention (PMC) Seasonal malaria chemoprevention (SMC) RTS, S Malaria vaccine	History Physical examination	Oral rehydration Antipyretics Immediate transfer to a higher-level health care facility
Referral Facility: General
Health education on prevention and treatment of Invasive Non-typhoid salmonella	Access to safe drinking water Use of improved sanitation Hand washing with soap Malaria prevention	History Physical examination Anthropometric measurement Complete blood count Malaria test HIV test Serologic tests	Oral rehydration salts (ORS) solution Antibiotics IV fluids Anti-malaria treatment Nutritional support
Referral Facility: Specialist
Health education on prevention and treatment of Invasive Non-typhoid salmonella	Access to safe drinking water Use of improved sanitation Hand washing with soap Malaria prevention	Blood culture Bone marrow culture Stool culture Lumbar puncture CSF analysis	Antibiotics Anti-malaria treatment IV fluid Nutritional support